Ho potlakisa litlhahlobo tse tšepahalang tsa mafu

Ho lieha ho hlahloba mafu a tšoaetsanoang beha baahi ba atileng kotsing lefatšeng la rona la lefatše, haholo-holo ka likokoana-hloko tsa zoonotic tse fetisoang lipakeng tsa liphoofolo le batho. Ho hakanngoa hore 75% ea likokoana-hloko tse 30 tse sa tsoa fumanoa tse tlalehiloeng lilemong tse 30 tse fetileng ka 2008 ke tsa liphoofolo, ho latela tlaleho ea WHO e lokollotsoeng ka 2021.

"Sehlopha sa rona se inehetse ho hlola liphephetso tsa moralo oa tlhahlobo ho sebeletsa tlhoko ea tlhahlobo ea lebelo la POCT le phihlello ho IVD ka bobeli (in vitro) le bao e seng IVD, "ho bolela Lianyi Xie, ea thehileng Hangzhou Bigfish Bio-tech Co., Ltd, ka 2017. "Liteko tsa rona tsa tlhokomelo ea tlhokomelo (POCT) li etselitsoe ho sebetsa ka potlako maemong a fokolang a mehloli, ha ho ntse ho etsoa lijo. bakeng sa mefuta e sa tšoaneng ea mafu.”

Li-POCT tsa Bigfish li etselitsoe ho sireletsa polokeho ea lijo, hammoho le bophelo bo botle ba liphoofolo tse ruuoang le liphoofolo tse tsamaeang le tsona, haholo-holo ha ho nahanoa ka palo e ntseng e eketseha ea beng ba liphoofolo tsa lapeng.

Litumello tse potlakileng tsa moralo oa POCT, Xie o hlalositse, li tlameha ho hatakela ho leka-lekana pakeng tsa boqapi le ho tsepamisa maikutlo ho thekenoloji ea setso le e tšepahalang ea amplification, e ipapisitseng le polymerase chain reaction (PCR), ho bona bongata ba metsotsoana ea nucleic acid ho tsoa mecheng e rarahaneng.

Nahana ka ho qhoma ha lefu la African swine fever (ASF) naheng ea China, lehae la 'maraka o moholo ka ho fetisisa oa tlhahiso ea nama ea kolobe lefatšeng ka bophara. Ka 2019, ASF e bakile lefu la likolobe tse fetang limilione tse 43, le tahlehelo e ka bang $ 111 bilione. Ho potlakisa meralo ea POCT ho itšetlehile ka tšebelisano e haufi-ufi le mekhatlo ea thuto le ea mmuso, hammoho le maikutlo a tsoang ho basebelisi, joalo ka barui ba likolobe ba ka sehloohong ba Chaena.

"Ho nepahala le kutloelo-bohloko ho ipapisitsoe le maemo a laboratori, esita le mapolasing a manyane a hole, ke tsa bohlokoa bakeng sa lisebelisoa tsa rona, tse entsoeng hore li rekoe ebile ho bonolo ho li sebelisa mohlapeng ofe kapa ofe oa likolobe," ho hlalosa Xie.

Mosebetsi oa Bigfish mabapi le thibelo le pheliso ea mafu naheng ka bophara o boetse o fetela ho brucellosis, e ntseng e le lefu le atileng haholo la zoonotic lefatšeng ka bophara, hammoho le mafu a liphoofolo tse tsamaeang le bona.

Bigfish e thusitse POCT ka potlako litsing tse ka bang 4,000 tsa bongaka ba liphoofolo ho pholletsa le China. Shuilin Zhu, molula-setulo oa Zhejiang Small Animal Protection Association, o ekelitse hore theknoloji ea k'hamphani bakeng sa liphoofolo.

leruo le tlhokomelo ea liphoofolo tse ruuoang lapeng ha se feela ho eketsa ts'ebetso ea thibelo le taolo, empa hape le ho ntlafatsa boiketlo ba liphoofolo haholo.

Ho lumella moralo o kopaneng ntle le litšenyehelo tse ngata ho basebelisi ke ntho e 'ngoe e tlang pele moralong le moetsong oa liteko tsa bona tsa lefutso. Tekolo ea bona ea limolek'hule GeNext ha e kholo ho feta botlolo ea metsi, 'me e boima ba lik'hilograma tse 2. E na le li-chips tsa mesofluidic le microfluidic tse tsamaisang mehato e boima ho tloha ts'ebetsong ea nucleic acid, ho phahamisa liphatsa tsa lefutso ho kenya le ho hlahloba data ka nako ea sebele.

E koaletsoe ka botlalo ho qoba tšilafalo e ka bang teng ea aerosol, GeNext 2.0 eo hajoale e hlahisoang ka bongata e ka etsa hore sampole ea tlhahiso ea sampole e eketsehe ho tloha ho 1 ho isa ho 16 ho pota, tatelano e lebisitsoeng e atoloha ho tloha ho 5 ho isa ho 25 ka lebelo, ntle le nako kapa litšenyehelo tse ling.

Xie o re: "Meralo ea rona ea GeNext 3.0 e tla fokotsa nako le ho feta, e ntlafatse ka lichifi tse thehiloeng ho silicon, 'me e kenye mahlale a tatellano a kang nanopore bakeng sa maemo a pharalletseng a tlhahlobo ea bokhachane le tlhahlobo ea mofets'e kapele. "Meralo ea rona ea POCT ka letsatsi le leng e ka sebelisoa ke mang kapa mang, kae kapa kae ntle le ho nahana ka litšenyehelo."